Showing posts with label apotek. Show all posts
Showing posts with label apotek. Show all posts

Monday, August 28, 2017

Valerian/ Læge-Baldrian/ Baldrian




Valeriana officinalis


Valerian (Valeriana officinalis, Caprifoliaceae) is a perennial flowering plant, with heads of sweetly scented pink or white flowers that bloom in the summer and can reach a height of 1.5 metres (5 ft). The fruits are nuts and the root system is a rhizome with numerous root tufts. Valerian flower extracts were used as a perfume in the 16th century. The flowers are frequently visited by many fly species, especially hoverflies and consumed as food by larvae of some lepidoptera, butterflies and moths.

Valeriana means "strong against diseases". The word valens means strong or fresh. The name might refer to a Roman herbal doctor named Valerianus who used the plant as a medicine. Other names used for this plant include Garden Valerian (to distinguish it from other Valeriana species), Garden Heliotrope (although not related to heliotropium Setwall and All-heal (which is also used for plants in the genus Stachys. Red Valerian, often grown in gardens, is also sometimes referred to as "valerian", but is a different species (Centranthus ruber) from the same family and not very closely related.




The valerian is spread in Minor Asia, Caucasus, Iran, Central Asia , Sibiria, East Asia and Europe. Valerian has been introduced into North America.  In Denmark it is spread in the eastern section but not seen in West- and North Jutland. The plant is found in shadowy or lightopen places with moist till wet or flooded soil - and is often seen in meadows or along water streams.

The plant and especially the rhizome contains several active substances: an etheric oil which together with valeren acid and isovalerian acid promote the very strong scent which is typical for valerian.  The plant contains also valepotriat and several alcaloids. The content of the valerian oil varies immensely in relation to the species, the age of the pant and the harvest time.



Folk Medicine


The rhizome contains valerian oil which is tranquillizing. The plant has been used against headache, muscle cramps, irritable colon and against wounds and exemia. Valerian tincture was used against bomb chok and other nerve strains during WWI.

The Valerian drops are used as a calming and somnolent means  and is sold as an OTC medicine. Laboratory studies point out that the plant might have anticancer effects. The root works calming and cramp loosening and can be used in nervous diseases and inner cramps.





Old herbal books recommend  to drink a glass of wine with valerian drops each day in order to maintain the health of the eyes and keep a sharp sight in old age; therefore the plant was named Eye root in the old days, which was due to observations of cats who had extended pupils when they had been rolling in the herb. An unusual feature of valerian is that valerian root and leaves are a cat attractant similar to, and as safe as, catnip. Valerian contains the cat attractant actinidine.  Stories describe the Pied Piper of Hamelin using both his pipes and valerian to attract rats.

Valerian has been used as a medicinal herb since at least the time of ancient Greece and Rome. Hippocrates described its properties, and Galen later prescribed it as a remedy for insomnia. In medieval Sweden, it was sometimes placed in the wedding clothes of the groom to ward off the "envy" of the elves. In the 16th century, the reformer  P. Marpeck prescribed valerian tea for a sick woman.


John Gerard's  Herball states that his contemporaries found Valerian "excellent for those burdened and for such as be troubled with croup and other like convulsions, and also for those that are bruised with falls." He says that the dried root was valued as a medicine by the poor in the north of England and the south of Scotland, so that "no broth or pottage or physicall meats be worth anything if Setewale [Valerian] be not there".

The seventeenth century astrological botanist Nicholas Culpeper thought the plant was "under the influence of Mercury, and therefore hath a warming faculty." He recommended both herb and root, and said that "the root boiled with liquorice, raisons and anisseed is good for those troubled with cough. Also, it is of special value against the plague, the decoction thereof being drunk and the root smelled. The green herb being bruised and applied to the head taketh away pain and pricking thereof."


                                         



From wikipedia:
Although valerian is a popular herbal medicine used for treating insomnia, there is no good evidence it is effective for this purpose, and there is some concern it may be harmful. There is no good evidence that valerian is helpful in treating restless leg syndrome or anxiety. There is insufficient evidence for efficacy and safety of Valerian for anxiety disorders.

The European Medicines Agency EMA approved the claim that valerian can be used as a traditional herbal medicinal product in order to relieve mild symptoms of mental stress and to aid sleep. The EMA stated that although there is insufficient evidence from clinical studies, the effectiveness of the traditional use of valerian is considered plausible when it has been used safely for this purpose for many years.

Because the compounds in valerian produce central nervous system depression, they should not be used with other depressants, such as ethanol, benzodiazepines, barbiturates, opiates, kava, or antihistamine drugs. Moreover, non-pregnant adult human hepatotoxicity has been associated with short-term use (i.e., a few days to several months) of herbal preparations containing valerian and scutellaria (commonly called skullcap). Withdrawal after long-term use in a male has also been associated with benzodiazepine-like withdrawal symptoms, resulting in cardiac complications and delirium.

The very limited animal and human data do not allow a conclusion as to the safety of valerian during pregnancy. Moreover, as a natural, unregulated product, the concentration, contents, and presence of contaminants in valerian preparations cannot be easily determined. Because of this uncertainty and the potential for cytotoxicity in the fetus and hepatotoxicity in the mother, the product should be avoided during pregnancy.


Source: Anemette Olesen Klosterurter, 2001, wikipedia 2017 
images: wikipedia

 

 

Valerian: Mechanism of action  (read information on wikipedia )






Danish information:
 Brøndegaard, Etnobotanik, Folk og flora bd. 4
Læge Baldrian/ Valeriana officinalis


Navne: Læge-baldrian, velandsurt (1546-1870) var vel opstået med allusion til sagnfiguren Vølund Smed; "katteurt" (1533-1789); "katterod" (1600t.) og "katteglæde" (1820), øjenrod (1648-1821), venderod/ vendelrod (1700t) den stærkt lugtende rod værnede mod hekseri, Danmarksgræs (1700t) plantens stængel med blomsterkvaster blev brugt af børn som slagvåben.

Saft af baldrian og pileblade blev brugt til salve på hævet strube, (begyndelsen af 1400t.)
Christiern Pedersen (1533): saft indgives mod epilepsi; vin- eller ølafkog af rødder var urindrivende, dekokt med fennikel og opiumvalmuefrø i vin eller øl drikkes mod lændesmerter.
Henrik Smid (1546): mellem de to fruedage 15/3 - 15/8 blev rødderne taget op og skyggetørret, den pulveriserede rod drukket med vin var urindrivende og hjalp mod gift og pest. Den friske urt knust og lagt på hoved stiller hovedpine. Øjne badet med vinafkog af rod og blomster bliver klare.
Simon Paulli 1648: den knuste rod indtaget med vin anbefales mod svagsynethed , heraf tilberedes også et øjenbadevand der blev solgt på apoteker. Nogle forfattere hævdede at planten eller en klud dyppet i dens saft kunne trække jern ud af hug- og stiksår.

Roden blev anført i farmakopeen in 1772. Den styrker senerne, er sveddrivende, fordeler svulster, lægges knust på sår og tørret i pose mod svage øjne. Roden har krampestillende, nervestyrkende, sved- og urindrivende og opløsende egenskaber, den modvirker hysteri og forrådnelse og anvendes mod indvoldsorm.  Den pulveriserede rod indgives for epilepsi. Mod hovedsmerter gnides panden med baldrianblade og krusemynte. Klog kone på Rømø gav den tørre, knuste rod som middel mod kvinders søvnløshed - eller de tørrede blade under hovedpuden. En te af bladene mod nervøsitet.
Roden indgik i en beskyttende pest-akvavit og et råd mod bl.a. feber og hjælper mod hudløshed. Indgik i øjenbadevand og "Herr Niels' dråber" = urteudtræk i brændevin


Husdyr


Baldrianrod er komponent i råd for oksens ondartede lungesyge og et røgemiddel mod kvægpest. Afkræftede kreaturer gnides med baldrian og tjære, "tjærespån og vendelrod - giver din ko god helsebod." Efter kælving skulle koen have baldrian. Roden af "katteurt" indgik i middel for hestens sygdomme. Får fik øldekokt af baldrian og stinkende kamille. Rod af baldrian, løvstikke og alant blev givet til syge svin. Baldrianrod blev brugt mod hundesyge. .  




Overtro
Baldrian eller St. Buldrian nævner ni andre helgener i flere signeråd fx "hil  dig San wenis urt = (Velands?) du er kommet af Jesu blod" (1692 og 1793) i lægeråd for at fremmane tyve , eller mod gæssenes forhekselse.  Hvis køerne omkring Mortensdag 11/11 fik baldrian i foderet, kunne de ikke forhekses. Rod af baldrian og mesterrod spises med kerner af pæon og nyserod mod trolddom.

"Mand og kone at forene som altid kives og trættes, giv dem begge et krus Valeriana, så bliver de straks gode venner."


Danish source: Brøndegaard, Dansk Etnobotanik, Folk og flora bd. 4: Læge Baldrian. 
images: grethe bachmann and wikipedia







Wednesday, May 18, 2016

The first Danish Apoteks - Mummy Powder and Scorpion Oil



Danish Apotek, 1700s
Medieval pharmacy
The Danish
apotekerskilt, Tønder, foto: gb
word Apotek comes from the Greek word apothéke which means storage or repository. (English: pharmacy).
The history of the Danish apotek is linked to the common cultural history.The medieval church was encompassing, the medieval Chapters were cultural centers with tasks in administration, education, justice and disease control. Far back in time church people were engaged in medicine and many of those are known by name. Many medical and herbal books were published, but most of them are lost. The development of the apotek/pharmacy is seen in the Pharmacopoeia (= the authorized lists of the medcine which an apotek had to hold). The Pharmacopoeia of 1772 is a turning point. Although some uneffective medicine still was accepted after this time  - like the scorpion oil - the deciding principle was from now on a medical science which rested upon experience, and the old folk-remedies had to give way. The change must be seeen in connection to the interest of natural science and the new discoveries which grew up in the 1700s.

Apotekerhaven, Viborg,


Already in the 1400s were the first traces of an independent pharmacy state in Denmark. Before the permanent apoteks were established, the medicine were procured in other ways. The relict flora by the Danish klosters show the cultivation of medical herbs,  but herbs were also imported and sold in common trade. In the Hanseatic tariff lists from 1368-69 are fx mentioned cloves, sapphron, cumin, poppy oil and ginger. Although some of it was sold as spice, a big part was probably meant for medicine. The border between medicine and spice was undeterminable, also later in time. The oldest Danish apoteks/pharmacies did not look like a pharmacy of today, they were storages and sales of medicine , herbals, details and much more, fx wine. A command from king Hans in 1510 informs that his pharmacist had to send some wine for the king's use.
Viborg Bymuseum
Not until late in the 1700s a more rational production of medicine began to build upon a practical scientific experience, but it never displaced the ineffective compositions and folk remedies, which had great confidence among people, like frk. Thunes balsam (Miss Thune's balm) which uncritically was used for all kinds of diseases and small ailments.  A detailed description was printed in a medical paper in Copenhagen 18 March 1767:  "This balm is a safe healing remedy for all appropiate, wounds by fire or boiling materia , or where the skin is scraped. It also cures frost-boils in hands and feet. It cleans and heals all deep wounds either if they are chopped, cut, encountered, even fistuleuse or desperates, when it is hot injected or injected in another way."





Mortars in the serpentine stone were used in the Danish apoteks since they would supposedly jump into pieces if they came in contact with poison.


Lapis-pin, Museum, the pin in the top is the hell-stone
The primitive stage of the pharmacy and medicine is also seen in king Chr. 6's medical history.  4-5 years before his death he had an abscess on the gums, which was treated with Lapis infernalis, helvedessten (hell's stone). His valet got the dubious task to treat the king, and it went completely wrong. The stone passed down the king's throat, and the valet became so frightened that he concealed the thruth. A borax powder could have saved the situation, but the valet was so scared of the king's eventual rage that he just advised him to take laxative in order to drive out the rest of liquid from the abscess. This accident might have been a cause of the king's later sickness and death.


Mummy Powder

One of the oddest medical remedies, which was popular from the 12th to the 18th century in Europe, involved powdering the remains of the ancient dead. Mummy powder was among the first of the old medicines which the new medical science rejected. Nevertheless this strange médicament  - like the scorpion oil - was used in Denmark almost up till present. In 1866 Assens Apotek (in Denmark) sold mummy powder, and still in 1927 a German medical firm sold mummy. Asphalt - which was used by the embalming  - was higly recommended as a medicine from old times, and it was probably the confidence in this substance which was transferred to the mummy medicine. The belief in the eternal conservation of the mummy was also a part of it. People might have imagined that the embalmed body contained a substance which might secure them something like an everlasting life. In accordance to this the mummy medicine was also the part of a powder which could help against death itself. In the later folk medicine mummy was together with other substances used in a means against dropsy. At the Danish Apoteks (pharmacies) mummy was sold in the name armesynderkød ( poor sinner's meat). Several samples of the fabric have been preserved, some contains without doubt real mummy, while others probably consists of asphalt.

Mummy. Louvre
Mummy powder was obtained by raiding ancient tombs and plundering the corpses found inside. These could include the most famous mummies in history, Egyptian mummies, or other less well known corpses. Once the corpse was obtained, it would be ground down into dust. The powder could be mixed with various other substances and was prescribed to treat everything from headaches, stomach ulcers, to tumors. It could be taken orally or used as a plaster or salve. It was so popular that any apothecary carried mummy powder among its stock. Humans weren't the only beings alleged to benefit from mummy; sick hawks were thought to benefit from their own grade of mummy powder.





Scorpion-oil
Ærø Apotek, Skorpionolie, Wikipedia
         
In ancient Danish medical books is mentioned a means against the poison of the scorpion - and this is obvious a loan from the South. In ancient times medicine against the scorpion's bite was sought after in the southern countries where the poisonous insect lived. Among the recommended means were some which used the animal itself as an antidote. The scorpion played a big role for the medical science up high in time, also in Denmark.
Common scorpion oil was produced by soaking 20 scorpions in oil from 1 pound of bitter almonds.

Besides this there was a medicine like the mixed mathiols scorpion oil for internal use which was used against plague-abscesses, smallpox, fever and paralysis. About year 1800 the scorpion slipped out from the part of the recommended medicine, but it lived on in folk medicine - and the scorpion oil was still sold at the Danish apoteks. In "Den gamle By" (Museum) in Århus is kept a bottle with scorpions found at Frijsenborg Apotek (established 1842) at the village Hammel. A pharmacist at Odder Apotek says in 1961 that it might still happen that someone asks for scorpion oil.
This medicine was from ancient times connected to the astrology. The scorpion gave name to a constellation, and it must be a reflection of this connection between medicine and astrology when the medical doctores at the University of Copenhagen were made responsible for making an almanac. The astrology had also its oppponents though, one was the archbishop in Lund (1201-23) Andreas Sunesøn, who said that "the stars do not show us future events as if man was in the happy possition of the gift of reason and was dependent on a star without feeling and life." Still today 800 years later some people might remember his sensible words.








Source: Danish Archaological Magazine: Skalk, nr. 2, 1961, Sundhed til Salg, Helge Søgård. 


photo from Viborg and Tønder: grethe bachmann
other photos from wikipedia.